Fertility Preservation as an Option for Women with Genetic Disorders: Insights from a SWOT Analysis on Elective Oocyte Freezing and Preimplantation Genetic Testing

This paper uses a SWOT (strengths, weaknesses, opportunities, and threats) analysis to overview the option of fertility preservation in women with genetic diseases, who would later use preimplantation testing for monogenic disorders, order not transmit their condition. Strengths associated elective oocyte freezing are ethical considerations, overall maternal fetal safety, effectiveness, if performed at <35 years age. Weaknesses related costs rare but present (<1–3%) risks complications. Counselling on management aimed preventing infertility offers valuable opportunity, same as it has been oncological patients’ care. The potentially high percentage conditions return frozen oocytes also represents an opportunity together minimization need egg donation, which higher obstetrical compared autologous oocytes. Finally, threat is represented by potential psychological distress young could never attempt become pregnant through testing, or do before any decline fertility. Potential unknown future long-term health children conceived after vitrification/thawing threat, current knowledge reassuring. Altogether, early counselling should thus be incorporated into standard care all patients